Is There a Way to Undo Radiesse or to Shorten It Lifespan?

There is little that can be done to undo or shorten the life span of Radiesse once it is injected. But since you didn't mention how long ago it was injected it may still be swelling that you don't like.  2 syringes of Radiesse is equivilent to less than a teaspoon of product so unless it was placed in a totally wrong spot it's hard to imagine it being too much product. It will probably look a lot better when the swelling goes down.

Radiesse is an FDA-Approved filler that we use very frequently in our office to sculpt the contours of the face. Since we are a national center of excellence for filler reversal, we also encounter patients from other doctors' offices who wish to have Radiesse fillers removed for one reason or another. In our office, we employ a directed technique to visualize the filler material, if possible on ultrasound, and then use non-surgical methods to dissolve the filler or granuloma tissue using intralesional injections. There are many methods using a combination of enzymes, intralesional modulators of scar tissue, and Kenalog to help reduce volume and remaining filler. These techniques require meticulous attention to detail and can be performed at intervals of two to three weeks to achieve longterm effect.

Best,
Dr. Karamanoukian
Realself100 Surgeon

   Unfortunately, Radiesse should be injected carefully, because there is no enzymatic degrading product.