Risk of Allergic or Toxic Reaction to Botox?

Although there is always a theoretical risk, I have never heard of an actual report of an allergic reaction to Botox. The product Botox contains ingredients other than the actual neurotoxin. Human albumin is more likely to cause a reaction, and again, I've never heard of it being a problem with Botox injections The risk appears to be low.

It is very rare to have an allergy to Botox. Although, I suppose it could happen.  I have yet to see one in my practice.