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Mixing tretinoin and adapalene for anti-aging, good or bad idea? (Photo)

Anders2Apr 14, 2018
I use tretinoin 0.1% every night but I find that using a peasize for the whole face + neck on dry skin is not enough, the recommended dosage simply will not cover the whole area. Yesterday I mixed my tretinoin with half a peasize of differin gel 0.1% and this made the spreading much easier. Is this OK to do or am I diluting/buffering the tretinoin and missing out on optimal results? I use the tretinoin mostly for anti-aging purposes. Kind regards.

Answers (1)

From board-certified doctors and trusted medical professionals
Dr. Martie Gidon, MD, FRCPC, FAAD
Certified Dermatologist
Answered on Jul 19, 2019
Answer
4 people found this helpful

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Karthik Ram, MRCS, DNB

Hi, Thanks for sharing your query. Tretinoin cream 0.025% is a very minimal dosage still it will have all the reactions which you have mentioned. Sun protection plays an important role in maintaining the effects of tretinoin. Kindly meet an expert to evaluate your skin. 

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If you are using retinoid creams, you may experience dryness and irritation that is commonly referred to as the ‘retinoid reaction.’ In our office, we recommend Elevase Moisture Booster to help reduce the dryness and to improve the skin’s natural moisture barrier function. Elevase contains ceram...

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Johnson C. Lee, MD

0.1% is stronger than 0.025%.Johnson C. Lee, MD Board-Certified Plastic Surgeon IG: @drjohnsonlee

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