Some swelling is expected after Radiesse injections. Icing the area for 10 minutes every 2-3 hours while awake the first 2 days after injections is helpful. I would limit physical exertion for the first two days as well.
What is important is the preparation beforehand. Unless prescribed by a physician, I ask patients to avoid any blood thinners, such as aspirin, other non-tylenol pain medications, vitamin E, fish oil, gingko biloba, for 10 days before injections. That decreases the risk of bruising.
Making sure that the injections are performed by a board certified dermatologist or plastic surgeon with proper training and experience in doing Radiesse injections.