After Radiesse injections, patients may have swelling, bruising, and redness. Other side effects are less common. Typical care would include use of ice packs every few hours for the first 24-48 hours, avoidance of blood thinners such as aspirin, motrin, ibuprofren, and naproxen, unless instructed to continue by your primary care physician, avoidance of vitamin E, fish oil, omega-3 fatty acids, and alcohol (which also thin the blood). Also, make-up application should be avoided the first 24 hours to prevent contamination of injection sites with bacteria present on make-up brushes and in the make-up. The skin should be cleansed gently as well with a mild cleanser. Sun protection is advised if the patient plans to go out in to the sun.