Safe to Put Juvederm in Lips After Silicone?

I have not had any complications injecting juvederm in patients who have had silicone in any location on the face.  Although many complications have been reported with silicone, there are no known chemical interactions between hyaluronic acid and an inert material such as silicone.  If there are contour deformities or other complications of the lips caused by prior silicone, these may or may not be temporarily correctable with juvederm.

There is no direct chemical intereaction between the Silicone you had and a new filler such as Juvederm or Restylane if it were injected. The Silicone is permanent and the hyaluronic acids just mentioned are temporary. There can be, and I have seen a reaction, of Silicone years later after the tissues near it are traumatized. There could be a disturbance of a biofilm and potential infection when a minimally invasive procedure such as injecitons are done near the prior Silicone. This is a theoretical concern. If you have the new filler, and you see months or even years later, a tender bump form, it could be the Silicone reacting, or a delayed response to the hyaluronic acid, but this would be very rare.

I am not sure if any study has truly evaluated the safety of using multiple different injectables on the lips and so I don't have a definitive answer but I do not believe this would be a problem.