Why am i still shedding after going through 3 PRP for hair loss treatments?

It’s understandable to be concerned about ongoing shedding despite completing several PRP treatments. While PRP therapy often helps reduce hair shedding and promotes growth, responses can vary widely between individuals.
Common reasons shedding may persist even after several PRP sessions include: • Natural Hair Cycle: Hair shedding may continue temporarily as weakened hairs transition out to make way for new growth. • Delayed Response: Some individuals experience noticeable reduction in shedding only after multiple sessions, typically 4–6 months into treatment. • Underlying Conditions: Conditions like hormonal imbalances, nutritional deficiencies, stress, or genetic factors can maintain ongoing shedding despite PRP treatments.
Given you’ve started noticing some new hair growth, this is encouraging. However, continued shedding suggests assessing and addressing potential underlying issues might enhance your overall outcome.
Consider discussing your progress and ongoing shedding concerns with your provider to ensure a comprehensive approach, possibly including blood tests or additional supportive therapies (such as vitamins, topical treatments, or medications).
I hope this clarifies your situation. A detailed evaluation by your provider or a hair-loss specialist can offer further personalized guidance.
— Güray Yeşiladalı, MD

Hello and thank you for your question. I'm sorry for your continued hair shedding despite treatment. There are many factors that can contribute to hair loss, and it may be worthwhile to have a comprehensive hair loss workup with labs if this was not done already. It is challenging to answer this without a little more context such as your age, gender, how long this has been occurring, recent stressors including illnesses as well as a full medical history. At our practice we typically order blood work prior to beginning treatment to identify if there are any other possible factors that can be addressed. This includes tests to rule out vitamin deficiencies, anemia, thyroid and hormone imbalances for example. I would recommend having a conversation with your provider about your treatment expectations. All the best, Esther Litenatsky AGACNP-BC on behalf of Dr. Ran Y. Rubinstein, facial plastic surgeon in Newburgh, NY and Montvale, NJ.

Although PRP is effective in preventing hair loss, ongoing effects of DHT to the hair follicles are not necessarily blocked or addressed. Hence, it may still present with ongoing hair loss/shedding.
I suggest incorporating treatment options that address DHT to help with keeping your current hair. You can also consider treatment such as minoxidil to increase capillary blood flow to hair follicle.