Why am i still shedding after going through 3 PRP for hair loss treatments?

Good question — and actually very common. Even after 3 PRP sessions, some shedding can still happen because hair grows in cycles, and PRP mainly helps strengthen and extend the growth phase. Shedding is often just part of that natural renewal before stronger hairs start coming in.
But before expecting PRP alone to “fix” hair loss, we have to go back to basics: the type of hair loss, your gender, age, medical history, and a few other factors all matter. If the root cause is androgenetic alopecia or another ongoing condition, PRP alone usually isn’t enough to stop shedding.
In such cases, a full treatment plan is needed. This might include medications like finasteride, minoxidil, or additional therapies like exosome injections, vitamins, minerals, biotin, and even hair transplant surgery— all depending on your diagnosis and condition.
So it’s not that PRP isn’t working — it’s that hair loss needs a more personalized, multi-step approach.

It’s understandable to be concerned about ongoing shedding despite completing several PRP treatments. While PRP therapy often helps reduce hair shedding and promotes growth, responses can vary widely between individuals.
Common reasons shedding may persist even after several PRP sessions include: • Natural Hair Cycle: Hair shedding may continue temporarily as weakened hairs transition out to make way for new growth. • Delayed Response: Some individuals experience noticeable reduction in shedding only after multiple sessions, typically 4–6 months into treatment. • Underlying Conditions: Conditions like hormonal imbalances, nutritional deficiencies, stress, or genetic factors can maintain ongoing shedding despite PRP treatments.
Given you’ve started noticing some new hair growth, this is encouraging. However, continued shedding suggests assessing and addressing potential underlying issues might enhance your overall outcome.
Consider discussing your progress and ongoing shedding concerns with your provider to ensure a comprehensive approach, possibly including blood tests or additional supportive therapies (such as vitamins, topical treatments, or medications).
I hope this clarifies your situation. A detailed evaluation by your provider or a hair-loss specialist can offer further personalized guidance.
— Güray Yeşiladalı, MD

Hello and thank you for your question. I'm sorry for your continued hair shedding despite treatment. There are many factors that can contribute to hair loss, and it may be worthwhile to have a comprehensive hair loss workup with labs if this was not done already. It is challenging to answer this without a little more context such as your age, gender, how long this has been occurring, recent stressors including illnesses as well as a full medical history. At our practice we typically order blood work prior to beginning treatment to identify if there are any other possible factors that can be addressed. This includes tests to rule out vitamin deficiencies, anemia, thyroid and hormone imbalances for example. I would recommend having a conversation with your provider about your treatment expectations. All the best, Esther Litenatsky AGACNP-BC on behalf of Dr. Ran Y. Rubinstein, facial plastic surgeon in Newburgh, NY and Montvale, NJ.

Although PRP is effective in preventing hair loss, ongoing effects of DHT to the hair follicles are not necessarily blocked or addressed. Hence, it may still present with ongoing hair loss/shedding.
I suggest incorporating treatment options that address DHT to help with keeping your current hair. You can also consider treatment such as minoxidil to increase capillary blood flow to hair follicle.

Shedding after PRP treatments is normal and part of the hair growth cycle. PRP stimulates follicles, but it doesn’t stop shedding immediately. Some people experience telogen effluvium, where old hair sheds before new hair grows. This shedding usually resolves after a few months.

It often takes 3-6 months for the full effect of PRP to show, so seeing some hair growth is a good sign. However, shedding can still happen while the hair cycle adjusts.

Check for underlying causes like stress, hormonal imbalances, or nutrient deficiencies that might contribute. After your 4th treatment, shedding may slow down. If not, consult your doctor.