Adequate removal of any tattoo depends strongly upon multiple tattoo characteristics. The use of picosecond lasers has been a new type of laser technology that aims to reduce collateral damage to the surrounding tissues. This is because a picosecond laser can generate a laser beam that is 1000x shorter than the conventional nanosecond q-switched lasers. There is some evidence to suggest that picosecond lasers can be more effective at removing recalcitrant (persistent) tattoos; however, conventional q-switched lasers also do a very good job depending on the tattoo. The Picosure laser is a picosecond q-switched Alexandrite tattoo laser that delivers a laser beam at 755nm. The Picoway laser is also a picosecond q-switched tattoo laser, but it is an Nd:YAG laser, meaning that it has the ability to fire a beam at 1064nm AND 532nm. Why does this matter? Traditionally, the most effective general-use wavelength for tattoo removal has been the Nd:YAG 1064 nm laser because it can target black and dark blue tattoos very effectively but still avoid pigmentation issues that can occur in dark-skin individuals (such as hypopigmentation). Once you switch on the 532 nm component, then you can remove red/yellow tattoos effectively as well. Despite this, the Alexandrite 755 nm q-switched laser has actually been shown to be more effective at removing dark tattoos than the Nd:YAG, but it has the ability to cause more pigmentation changes and skin injury due to its wavelength; in addition, it is also unable to address red-colored tattoos adequately. For most amateur and dark tattoos, both lasers, being picosecond lasers, should do a very good job, so I think that you will probably be happy with either of them regardless. If you have a red-colored tattoo or you have dark skin, then the Picoway laser might be best. Best of luck with your search!