Is Sculptra Safe for People with SLE and APS?

I have SLE and APS for years, it's under control but I'm still on medication . Would like to know is Sculptra safe for people with SLE and APS? Is it true that people with SLE will have a higher rate of formation of true granulomas? One aesthetic doctor told me it's fine to have Sculptra done but there are other doctors who advise not to.

Doctor Answers 4

Is Sculptra Safe for People with SLE and APS?

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}

Thank you for your question. The safest thing to do is to have nothing injected.  You have to determine how much risk you want to undertake, and how important the cosmetic improvement is worth to you.  No procedure or injection is zero risk.  Thus, you have to decide what risk you want and the value of the benefit. No one will know with 100% certainty, what will happen. I hope this helps!

Sculptra has been shown to have more granulomas in patients with autoimmune disease

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}

With retrospective analysis, people who developed granulomas after Sculptra injections were disproportionately more likely to have an autoimmune disease than ones without granulomas.  In reality, very few people actually develop granulomas.  It has been recommended by the company not to inject a person with autoimmune disease like SLE but it is still safe.  The theory is that the immune system is not normal and the reaction to the Sculptra is not predicatable with some over reacting and cause granuloma formation.  It's something you need to discuss with your physician and decide amongst yourselves.

Steven F. Weiner, MD
Panama City Facial Plastic Surgeon
4.9 out of 5 stars 75 reviews

Is Sculptra safe in patients with Lupus(SLE)?

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}


Since Sculptra works via stimulating your own collagen to develop in areas where it has been injected, I would shy away from Sculptra if you have a history of lupus. I have personally told patients with lupus that I would not choose Sculptra since having a complication of granulomas or a lupus flare is not worth trying to obtain an aesthetic result.  Your health is always more important than a cosmetic complication.



Dr. Liu

Grace Liu, MD
Newport Beach Dermatologic Surgeon
4.9 out of 5 stars 52 reviews

You might also like...

Sculptra safety

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}

In general, Sculptra (PLLA) is a very safe product with very few side effects when properly injected.  Granulomas or nodules are very uncommon when the product is injected in the proper plane. In very rare situations, a granulomatous response is found.  Because the frequency of injecting this product in immune compromised patients is low, it is unclear if the incidence of granulomas is increased in patients with SLE.

Jonathan Sykes, MD
Beverly Hills Facial Plastic Surgeon
4.5 out of 5 stars 28 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.