The active ingredient in Latisse which grows lashes is Bimatoprost, a prostamide, a prostaglandin analog which lowers eyeball pressure in patients with open-angle glaucoma. When patients using Lumigan eyedrops for glaucoma began having longer lashes a lot of doctors began prescribing the medication to people who did NOT have glaucoma -- for cosmetic reasons. Several make up companies, including Jan Marini Skin Age Intervention Eyelash Conditioner, Athena Cosmetics Corp. - RevitaLash, MassiveLash, and MD Lash Factor , began selling eyelash products allegedly secretly containing Bimatoprost, the active ingredient in Lumigan®. Allergan, the maker of Lumigan and owner of the license to Bimatoprost sued them for millions and the cases were settled with these companies promising to remove the Bimatoprost from their products. Therefore, Revitalash no longer contains Bimatoprost and does not compare to Latisse in effectiveness. Applied to the edge of the upper lid without direct application to the eye means you have a VERY small risk of eye color changes.