Restylane Injected in Lips, Have Bumps on my Lips When I Smile. Look Like Blisters. Will it Subside?

Question

I had Restylane injected in my lips April 11, this is Day 15.. I have bumps on my lips that are noticeable when I smile. Looks a little like blisters but when I rub my tongue over my lips they feel like hard knots. Will this sub-side and how long should it take?

Nima Shemirani, MD · Answer

Hi @Tracker RN. Based on what you are describing, the filler was placed too superficially. I recommend dissolving the product with Hyaluronidase. Best of luck, Dr. Nima!

Sam Naficy, MD, FACS · Answer

If you've experienced raised bumps in the lips post-Restylane treatment, I'd absolutely return to the provider to have those removed with Hyaluronidase. It's not common nor uncommon to have this happen and is easily treated!

Jonathan Kulbersh, MD · Answer

It is difficult to give you advice without seeing your lips in person. Bumps following Restylane injections are rare, but may be caused if:

	1) The Restylane was injected superficially, or too close to the surface of the skin
	2) Too much was injected
	3) The Restylane was injected unevenly and/or with poor technique

	In general, these lumps can be massaged out if they are addressed within 24 hours of the initial injections. In cases where the patient wishes to eliminate filler in an area before the body takes care of it on its own, the enzyme hyaluronidase is a great option.  The enzyme can dissolve the filler, leaving the patient without a trace of it. Depending on the exact nature of your issue, this may be an option.  I would recommend seeing your physician who performed the injections, and discussing a possible treatment for your issue with him or her.  Thanks and good luck!

Steven Hacker, MD · Answer

Unfortunately, after certain injections, particularly if superficial may result in small white bumps. If these do not dissolve, then you should show them to your dermatologist for treatment options.

Marianna Blyumin-Karasik, MD · Answer

Dear Patient,

	It is disappointing to see and feel bumps on the lips after Restylane treatment. Although rare, this can occur if the material is injected superficially. If these bumps have not resolved after 2 weeks, then its unlikely that these are temporary bruises and more likely to be a superficial deposition of hyaluronic acid. I would recommend to visit your cosmetic provider and consider hyaluronidase treatment to dissolve these bumps. Good luck.

Restylane Injected in Lips, Have Bumps on my Lips When I Smile. Look Like Blisters. Will it Subside?

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Answer: Bumps like blisters on lips after Resylene

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Restylane Injected in Lips, Have Bumps on my Lips When I Smile. Look Like Blisters. Will it Subside?

Answers (6)

Answer: Bumps from Restylane

Answer: Bumps from Restylane

Answer: Bumps like blisters on lips after Resylene

Answer: Bumps like blisters on lips after Resylene

Browse related questions

Recommended reading

Everything you need to know about Restylane

Our mission is to create a world where every investment in modern beauty is Worth It.