Can Restylane Cause Enlarged Oil Glands on Face?

Question

I had 1cc of Restylane injected into one side of my face 8 weeks ago. Now I have at least 10 enlarged oil glands on that side of my face but only had 2 before. None on the other side of my face. What is going on? I know they are enlarged oil glands not pimples or moles etc. Does the Restylane prevent the skin from functioning properly? Concerned about Hyperpigmentation if I have them removed - what would be the best course of treatment? Thank you!

Ron Shelton, MD · Answer

sebaceous hyperplasia, or enlarged oil glands around pores do not get produced suddenly from Restylane or Juvederm injections. could these possibly be some other kind of bumps? You should see your doctor to examine these bumps and see if there is a good treatment for them.

Trevor M. Born, MD · Answer

Dear CS122,

	Thank you for your question.  I have not seen this before- but in Medicine anything can happen, Restylane is a good product- its safe, has good longevity and can be removed if needed (last resort).  You should return to your MD for a check up.

	With Warm Regards,

	Trevor M Born MD

Robert A. Weiss, MD · Answer

Restylane does not cause the enlargement of oil glands (sebaceous hyperplasia). Enlarged oil glands, sebaceous hyperplasia, tend to be genetic and found more commonly in those with skin on the oily side. Sebaceous hyperplasia can be treated with lasers like SmoothBeam. The use of a Retin A product can help to keep more from forming. Your bumps may also be from Restylane being injected too superficially. I recommend that you check with the practioner who treated you.

Peter L. Kopelson, MD · Answer

Oil glands (sebaceous glands) become enlarged largely due to genetic predisposition. Nothing (such as Restylane) will provoke this change, and although it cannot be prevented it is easily treated by a dermatologist.

Deborah Sarnoff, MD · Answer

Restylane is one brand of injectables - hyaluronic acid. It does not cause enlarged oil glands. When Restylane is injectedin the skin to fill lines and wrinkles, they smooth out very nicely. It is possible that because the skin is smoother, without wrinkles for your eye to focus on, you can now see the texture of your normal skin more clearly than beefore and you might interpret your normal pores as enlarged glands.

Steven Wallach, MD · Answer

Restylane is a great product to improve facial depressions.  If it is injected too superficially it may dilate the skin a bit and accentuate the pores. Go see your doctor and get re-evaluated.

Hassan Galadari, MD · Answer

Though not been reported in the literature, you should be seen by the doctor who injected you initially to see what the cause is and what can be done about it.

Michelle R. Yagoda, MD · Answer

Dear CS 122,

	Without examining you, it is not possible to properly diagnose you.  However, when Restylane is injected too close to the surface of the skin, you may see whitish bumps.  You should return to see the doctor who injected you for proper advice and treatment.

	Best,

	Dr. Yagoda

Jeffrey C. Poole, MD - Account Suspended · Answer

The condition you are referring to-- sebaceous hyperplasia-- is commonly seen in sun-exposed areas of the face.  I have never seen this develop with any Hyaluronic Acid Filler, such as Restylane or Juvederm, and have not seen any reports in the medical literature.

	For evaluation and treatment, see your Board Certified Treatment.  Therapy is often quite simple with light electro-cautery.

Eugene Mandrea, MD (retired) · Answer

It is impossible for Restylane (Hyaluronic acid)  to cause enlargement of oil glands.

	I assume you are talking of enlarged oil gland openings. This can happen following  injection of almost any filler  if done too superficially. It usually subsides with time when caused by Restylane.

	It would be  best to see the practitioner who injected it. If indeed an excessive amount of  Restylane has been injected too superficially, a small dose of Hyaluronidase (an enzyme that disolves the Hyaluronic acid) may resolve the matter in a few days.

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