Can Restylane and Botox Be Applied Safely in Different Areas at the Same Time?

It is very common to have Botox between the eyebrows done at the same time as Restylane in the nasolabial folds.  Please be evaluated by an experienced injector.

It is not only OK, but quite common nowadays among experienced injectors to combine various fillers, such as the hyaluronic acid fillers Juvederm and Restylane, with calcium-based volumizers, such as Radiesse. Depending upon the location and the need, these products are sometimes even mixed within the same syringe. A tiny amount of Radiesse, a whitish colored material, added to Juvederm is particularly useful for lightening undereye dark circles while softening bags and tear troughs under the eyes.

Likewise, the use of neuromodulators, like Botox, Dysport, and Xeomin, are also frequently employed at the same time as fillers and volumizers when there is both a need for softening facial muscular action and treating the creases, the etch-like marks, that are left in the surface of the skin from years of folding thousands of times a day. I have found this combined approach particularly helpful in treating the scowl (frown) lines between the eyebrows and worry lines across the forehead. I first treat the etched creases with a superficial filler, such as Juvederm to raise them to the surface, and then follow this with Botox or Dysport. The superficial lift to each crease generally yields an immediate gratifying response, which is further enhanced within a few days when the muscle-relaxing effects of the neuromodulator take effect. Minute droplets of both filler and Botox placed superficially in a grid-like pattern can also be helpful for smoothing the otherwise difficult to treat prune-face-like wrinkling seen on the lower cheeks and around the chin in some individuals .

It is extremely common for patients to get their Botox and fillers, whether Juvederm, Restylane or Radiesse, injected during the same visit with good results. If I inject the same site, then I inject the filler first and then the Botox so the botox won't be displaced by the pressure of the filler.