Dear Saint Clair Shores
BOTOX, Dysport, and other Botulinum toxin preparations are safe for the 11 lines area between the eyebrows. The treatment is extremely safe and proven effective. It is possible to inject into a blood vessel in this area, and the tiny amount of agent that will get into the blood stream is not associated with systemic side effects. Even the FDA which recently required so-called black box warnings which for Botulinum toxin agents, has said that Botulinum toxin used for cosmetic purposes including the 11 lines is safe and has not been associated with systemic complications. The black box warnings were required because doctors have been using very high doses in sick infants with complex medical problems and this has been associated with systemic complications including death. Important to understand that so much in medicine is a question of dose. Two acetaminophen helps your headache but 200 acetaminophen damages your liver.
Different story for fillers. The injection of fat into the glabellar area has caused embolic stroke and death. Other fillers including hyaluronic acid fillers injected into this area have caused central retinal artery occlusion with visual loss and blindness. More commonly, these injections can damage collateral circulation in the glabellar area causing skin necrosis in the glabella and as far away as the tip of the nose. Consequently injection in this area must only be done in the epidermis or not at all.
If you are planning BOTOX or Dysport injection for the 11 lines, this is very safe and does not affect the circulation-relax. However, the best advise is to avoid having well meaning injectors place filler in this area the risk of this procedure is real.