If Radiesse is Dissolved, then the Problem is in Biopolymer Gel? Whether is Not That's Problem?

   The name of the first product would be helpful.   This periodic reactivation is curious and points to a dormant phase, which may be indicative of fungal or mycobacterial cause.  There could be a viral component as well. If the reactivation occurs again and there is anything to culture, I would recommend this.  In addition, particular nodules may need to be excised.  Please followup with your plastic surgeon to address these concerns.

This is very difficult to sort out without examining you and knowing exactly where things were placed. Intermittent swelling can be caused by many things including MSG or sodium in your diet causing you to retain fluid.  There may be other issues contributing to the problem.  My recommendation would be to see your medical provider and let them help you sort this out.

It would be interesting to know what material was initially injected into your cheeks. The normal inflammation caused by your second injection could activate granulomas, nodules, and biofilm, especially if a permanent filler such as ArteFill is present in the same area. If a bacterial biofilm forms, hard, red, painful and sometimes oozing nodules can develop. These reactions can occur years after the initial injection. I would return to your injector to be evaluated for biofilm. Treatment usually required long term antibiotics. For this reason, I will never inject any filler in an area that was previously injected with permanent fillers or silicone.

Radiesse typically lasts about 6-18 months, though it can take longer for it to degrade and resorb.  I suspect that the problem is from whatever was injected the first time, although it is obviously difficult to make that assessment via this forum.  You'll need to be seen and treated in person, but certain substances that are injected, including permanent non-medical materials, can prove troublesome.  Sorry,

Dr. E