Can Radiesse Complications Be Reversed?

I am planning on getting treatments for my mouth lines( which are pretty deep) My Dr recommended Radiesse which I am ok with. I am just afraid that if something long term goes wrong ( he has never had that problem) that any swelling or redness ( without prednizone) can be reversed. I have only read one bad story but it concerns me.

Doctor Answers 14

Radiesse has a good safety profile

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Although Radiesse has a good safety profile, I'm not sure what you mean by mouth lines. If these are the smile creases that run from the corner of the nose to around the corners of the lips, then you have a greater track record of safety than if the RAdiesse is used to try to fill in deep upper (cutaneous - lip colored, not the vermillion or red lip) lines than run vertically from the edge of the red lip to the bottom of the nose (called smokers lines by some). In the latter area there is a greater chance for the Radiesse to cause lumps in the red lips.

NO filler is without some chance of risk. Thick fillers such as RAdiesse can cause a problem but very very rarely with circulation when injected in the smile crease near the corner of the nose and skin changes have occurred with possible scar formation although many of these rare events have healed well. There is no reversal of this or a lump that is noted later with Radiesse compared to the dissolving that can be done with Restylane or Juvederm by using hyaluronidase.  Overall, as you have confidence with your doctor who is very experienced, after you discuss your concerns with them, the two of you can decide to proceed ahead if you still feel comfortable knowing the risks. The numbers of procedures done with Radiesse are evidence of its great safety profile.

Manhattan Dermatologic Surgeon
4.9 out of 5 stars 38 reviews

Radiesse is not reversible like Juvederm or Restylane

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Radiesse is a calcium based filler.  It’s not reversible like Juvederm or Restylane.  For lines around the mouth, you have to be very careful using Radiesse.  For marionette lines that are deep, Radiesse works well.  But, for fine lines around the mouth, it can get lumpy.  If the doctor has a lot of experience with Radiesse, however, you can get very nice results.  It depends on how you dilute the Radiesse.  As far as reversibility and bumps, you certainly are safer around the to use juvederm or restylane around the mouth.  These products are reversible and less likely to to cause lumps.  If, you do get a bump or problem with Radiesse, it does eventually go away, but it can take a long time.  You can inject it with a steroid to break it up, but it doesn’t always work very well.  If you’re going to use Radiesse around the mouth, make sure your doctor has a lot of experience, otherwise, choose a reversible filler like Juvederm or Restylane.  You should also realize that all these applications for these products are “off-label”.

Mouth lines with radiesse

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I'm not sure what you mean by "mouth lines" but assume you mean those around the lip. If so, I would prefer to use a softer filler such as Restylane or Juvederm. If you mean the lines in the corners of your mouth I think that Radiesse might be a good choice but if you are worried go with Juvederm or Restylane  which last less long and can be dissolved. 

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Radiesse Complications- Reversible?

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The biggest issues with Radiesse are poor filler placement or the creation of palpable nodules.  Both of these issues are not correctable.  It is important for patients to understand that any injector, particularily an injector of Radiesse, should be highly skilled technically, have knowledge of facial anatomy, and understand facial aging and beauty.

Anil R. Shah, MD
Chicago Facial Plastic Surgeon
4.8 out of 5 stars 171 reviews

Radiesse for lip lines

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In my opinion, I would stay away from Radiesse for lipstick or smoker's lines because of the thickness of the product and the lack of fat in this area.  I never use it there.   I think it would be too lumpy and not easily corrected if you did encounter a problem.  I generally prefer hyaluronic acids like Restylane or Juvederm in this sensitive area which can be dissolved with Hyaluronidase if there are any contour issues.   Other options to treat these lines include Botox which of course is temporary.  Combining Botox with Restylane is a more effective method to treat these lines than either alone.  More lasting correction of lipstick or smoker's lines can be achieved with dermabrasion, chemical peels or CO2 laser.   These treatments do have some downtime but over the most natural, long lasting results. 

James C. Marotta, MD
Long Island Facial Plastic Surgeon
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Reversal of Radiesse Complications

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In experienced hands, Radieesse complications are rare when injected into appropriate areas of the face. I personally prefer to use hyaaluronic acids like Juvederm and Restylane adjacent to the lips and at athe lower eyelid margins.

Richard W. Fleming, MD
Beverly Hills Facial Plastic Surgeon
4.9 out of 5 stars 40 reviews

All fillers have the potential for causing bad results.

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All fillers have the potential for causing bad results. As Harry Truman said if the kitchen is too hot stay our of the kitchen.

Edward Lack, MD
Chicago Dermatologist

Radiesse precautions

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Radiesse is a FDA approved filler based on refined calcium granules that serve as nice scaffold for collagen production and temporary volume replenishment. Unfortunately, it cannot be reversed if there is nodularity performed by an inexperienced injector; however it will fade over 9 months. In the hands of experienced physician injector for nasolabial folds, I believe Radiesse may offer the best value for the investment.

Radiesse complications

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Radiesse complications such as lumpiness, or over-filling should resolve once the filler dissolves, but are not reversible in the short-term.  I generally do not suggest Radiesse be used in the vertical lip lines.  Radiesse especially should not be used in the vermilion (red portion) of the lip.  If you are concerned about the possibility of Radiesse-related complications, you may be better off going with one of the hyaluronic acid fillers (Restylane, Juvederm) which can easily be dissolved with hyaluronidase.

Bryan K. Chen, MD
San Diego Dermatologist

Radiesse for lip lines

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Personally, I'm affraid of Radiesse for lip lines around the mouth.

I am sure there are some excellent plastic surgeons or dermatologists who can  get good results, but even in their hands the results can vary from patient to parient. Also, the longevity of the results can vary.

I would feel much more confident with any Hyaluronic Acid compound (Prevelle,Restylane, Juvederm, in order of longevity). In facti, I would start with the shortest acting, Prevelle, to have you see how you like it and take it from there.

For the best and  longest lasting results, I recommend small doses of Botox injected in the muscle (Orbicularis), followed 5 to 7 days later with Traditional Laser Resurfacing (this latter has 7-9 days down time).


These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.