Botox alternatives for forehead lines? (Photo)

Hi! Dr Peterson here – that’s a really thoughtful question and I completely understand where you’re coming from. If Botox or other neuromodulators aren’t an option, there are still treatments that can help soften forehead lines. Resurfacing lasers (like fractional CO2 or erbium) or microneedling with radiofrequency can stimulate new collagen and smooth etched-in lines over time. Chemical peels and medical-grade skincare with retinoids can also improve fine lines gradually. For deeper wrinkles, sometimes hyaluronic acid fillers or biostimulatory injectables are used very cautiously in the right patients to support the skin, but it depends on your anatomy. None of these work quite like Botox, but a skilled dermatologist can put together a plan that helps you feel refreshed without using neurotoxins.

Small amount of a filler(I recommend Volbella) should improve the appearance of the forehead lines. I recommend using 1 syringe of Volbella to begin with.

There are a few alternatives you can use to help with forehead wrinkles since Botox is not an option for you. You can concentrate on improving the skin texture with treatments such as lasers or Morpheus8. You can also consider chemical peels. We always recommend using medical grade skin care products such as Transform MD and wearing sunscreen every day.

You’re absolutely not being petty — forehead lines affect both appearance and confidence, and it’s normal to want solutions. Since your neurologist advised against neuromodulators like Botox, there are still effective options.
Non-toxin alternatives include:
Morpheus8 (RF microneedling): Boosts collagen and tightens skin to soften forehead creases.
Microneedling with PRP: Improves texture and helps smooth fine lines naturally.
Laser resurfacing (CO₂, Erbium, fractional): Targets deeper etched-in lines.
Chemical peels & prescription skincare (like retinoids): Support gradual smoothing and skin renewal.
These treatments work by stimulating your skin’s own healing and collagen production, rather than relying on muscle relaxation. With the right plan, you can still achieve smoother skin and feel more like yourself.

Thank you for sharing your concern. Since your neurologist has advised against Botox due to your neuromuscular condition, there are still several safe alternatives that may help soften forehead lines without the use of neuromodulators or neurotoxins:

Topical Treatments

Retinoids (such as tretinoin or over-the-counter retinol) help stimulate collagen production and improve skin texture over time.

Peptides and growth factor–containing creams may help support skin firmness.

Antioxidants like vitamin C serums can protect against free radical damage and brighten skin.

In-Office Procedures (Non-Neurotoxin Based)

Microneedling: Stimulates collagen production and improves fine lines and wrinkles.

Laser resurfacing (such as fractional CO₂ or erbium lasers): Can improve skin tone, texture, and reduce the appearance of lines.

Chemical peels: Promote skin renewal and smoothness.

Radiofrequency or ultrasound-based skin tightening (e.g., Ultherapy, Thermage): Stimulate deeper collagen remodeling.

Dermal Fillers

In certain cases, hyaluronic acid fillers can be used strategically in the forehead area to soften deep lines, though this should be done cautiously and by an experienced injector.

Lifestyle & Supportive Measures

Daily use of sunscreen to prevent further damage.

Good hydration, a healthy diet, and sleep optimization.

Avoiding smoking, which accelerates skin aging.

While Botox is the gold standard for forehead lines, these alternatives can still provide meaningful improvements and help restore confidence safely in your case.