5th week on oratane, still no improvement! What to do?

Thank you for your question. It is not uncommon to have breakouts when starting any acne treatment, especially Accutane. Usually the flare-up lasts a couple of weeks, but in some individuals, the flare-up can be very severe and occur for several months. Breakouts also vary depending on the dose you are taking. Please be patient with the treatment because acne tends to get worse before it gets better. I highly suggest you consult with your prescribing dermatologist regarding your concerns and to discuss any further questions you may have with therapy. Take care and good luck.