Ultherapy overall is a well tolerated procedure. It can be done in the office and can be done with no means of chemical pain control (e.g. nerve blocks, anxiolytics, narcotics) That doesn't mean it is a walk in the park. I have personally tried Ultherapy and did one half with no pain control and used nerve blocks on the other half. I would rate my overall discomfort level as 5/10. However, there were times when it was a 2-3/10 and other times when it was 7-9/10. After the procedure, I had minimal discomfort and started seeing patients. The numbing definitely made the treatment more comfortable, but I had several hours of feeling like I've been to the dentist on half my face.
For my patients, I offer talk/music/distraction therapy (i.e. no chemical intervention), nerve blocks, or if they have someone to drive them home, they can take an anxiolytic (e.g. Ativan) and/or a narcotic.