Post mastectomy pain and chest wall tightening with seroma (Photo)

I'm sorry you are suffering! Placing tissue that has had no radiation exposure at the site may help considerably. It will improve drainage and decrease tightness. It means more surgery, but it may give you relief. This would be a DIEP or latissimus flap. Talk with your doctors about these options. 

I am so sorry to hear of your post mastectomy/treatment pain. The combination of surgery and radiation may worsen pain and seroma from either alone, and cause tightness which may be disabling. In addition to pain meds including gabapentin (neurontin for nerve pain), and antiinflammatories (advil) physical therapy is frequently helpful in stretching the skin and improving strength and mobility of the arm and shoulder. Patients have also found accupuncture and massage therapy helpful. Good luck and take care.