How can I remove Restylane in my jowls that is more than two years old and spread out?

Thanks for your query. The Restylane generally don’t have the side effects of swollen lymph nodes, headaches, sinuses or headaches, the main side effects from restylane are minor head ache, localized swelling at the area of injection, bruising, etc. If the restylane is now old and generalized, then you can just go for rf or ulthera, or exilis. This dissolves the filler and through lymphatic channel, it’s removed from the system. Hope it helps.All The Best

restylane has been shown to last from 6-12 months. It would not be the norm to still have product in the area after 2 years. What's nice about the hyaluronic acid fillers is that they are temporary and they are reversible with hyaluronidase. So if you feel the product is still there, and tests have proven it is, I would dissolve it out with hyaluronidase. But this would be very unusual. 

Restylane is a temporary, hyaluronic acid-based filler that is reabsorbed by the body gradually over time.  It would be extremely unusual for Restylane to be present after two years and to cause the issues you have described.  Contact the physician that performed your injections and ask for hyaluronidase, which dissolves Restylane.

It is very unusual to have restylane present after two years. You can dissolve Restylane. See a dermatologist or plastic surgeon that uses fillers and discuss dissolving this if it is really still there.