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Does PRP/PRF cause or reduce inflammation? Can I have PRF Microneedling 2 weeks after PRF injections?

MediKateJan 19, 2023
I'm reading very conflicting things about PRP/PRF treatments and whether they cause inflammation or reduce it. I had PRF injections to my face almost 2 weeks ago and am about to have microneedling with PRF, but am now worried it might be too soon as there might still be some inflammation. I'm also not sure whether the collagen is broken down by any of these treatments, so if it's better to wait until a full month has passed in order for the collagen to rebuild.

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Dr. Jeff Rapaport, MD
Dermatologic Surgeon, Board Certified in Dermatology
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Answered on Jan 22, 2023
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Devin Stone, ND

Yes, PRP should be a safe modality for you. This will still take proper assessment by your provider. Since PRP works to naturally stimulate natural healing processes. PRP can also be used as a collagen stimulator in areas where fillers would be used. Typically a series of three treatments one...

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Arslan Musbeh, MD

You’re asking an excellent question — timing is indeed crucial when using PRP (Platelet-Rich Plasma) for post-laser or thermal injury recovery. If the skin shows acute inflammation (redness, sensitivity, peeling), it’s best to allow at least 4–6 weeks for natural recovery before applyin...

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Jeff Rapaport, MD

You are correct. The density of the gel that is injected with PRF has the potential to cause a vascular occlusion or blindness. Several documented cases appear in the literature. For this reason, I believe it's safer to inject plain PRP. Find a PRP expert. Jeff Rapaport MD FAAD Realself Hall...

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