Thank you so much for a great question. I personally use both Silhouette Soft and PDO threads, and find that both have their place. Some key differences are:- The material they are made out of: PDO stands for Polydioxane whereas Silhouette Soft are made from PolyLactic Acid. Both have excellent safety profiles- How they lift?: Silhouette Soft have cones along the length of the thread, allowing suspension of the tissues. PDO cog threads have tiny barbs which anchor in the facial ligaments- The technique: The insertion of the threads is different, and important.Both techniques have their place. I find PDO particularly helpful in patients who have heavy or thicker tissue, whereas Silhouette Soft is excellent for facial contouring and repositioning of volume. We would always recommend having a consultation with a doctor who uses both techniques who would be able to recommend which product would be best for you. Hope this helps to answer your question.