Can you become immune/resistant to Accutane?

While it is uncommon to develop resistance to Accutane (isotretinoin), there are several factors to consider if you're experiencing a return of symptoms like redness and itchiness:

Understanding Isotretinoin:

Accutane works by reducing the size and activity of sebaceous glands and has anti-inflammatory properties. It is not an antibiotic, so the concept of "resistance" as with antibiotics doesn't apply.
Recurrence of Symptoms:

Some individuals may experience a recurrence of symptoms after completing a course of Accutane. This does not indicate resistance but rather that the underlying condition may require ongoing management.
Possible Causes of Redness and Itchiness:

These symptoms could be side effects of the medication itself, as Accutane can cause skin dryness and sensitivity.
External factors, such as environmental changes, skincare products, or lifestyle habits, might also contribute to these symptoms.
Management and Consultation:

It's important to discuss these symptoms with your dermatologist. They might adjust your dosage, recommend supportive skincare, or explore other treatment options.
Ensure you are using gentle, hydrating skincare products and protecting your skin from sun exposure, as Accutane increases photosensitivity.
By consulting with your healthcare provider, you can find strategies to manage these symptoms and explore whether adjustments to your treatment plan are necessary.