Can I Mix Hydroquinone with Tretinoin and Moisturizer?

There are many different types of moisturizers. In our office, we advise patients using Retin A to combine the cream with Elevase Moisture Booster with opti-ceramides. Best, DR. Karamanoukian Los Angeles

As you may or may not know, Triluma is a combination of fluocinolone acetonide (steroid), tretinoin and hydroquinone and which when used daily can help to improve discoloration and skin conditions like melasma. The combination of the three is very effective, but Triluma can be difficult to find and very expensive. So to answer your question, you can mix your hydroquinone and tretinoin with moisturizer and apply it nightly.  You could also just mix the hydroquinone and tretinoin together, apply that  mixture, and then apply your moisturizer over.  Better to apply them at night as tretinoin can be irritating in the sun. Make sure to wear sunscreen as the sun will only continue to worsen the melasma.