My skin graft changed appearance overnight. Is this normal? (photos)

Judging by the picture, your graft looks fine. I don't see any cause for alarm. If you still feel uneasy about how it looks after the weekend give your dermatologist a call to be seen.Thank you for your question and for sharing your picture!

I do not see anything that causes me alarm from your photo. What you probably had before was a lot of bruising (very common in the nose) and so that is going away. The pink tissue is new skin forming and the graft (good signs) and the brownish goo, is that part still healing. I would continue to keep the site clean (obviously) and well moistened with Vaseline or Polysporin or whatever your surgeon suggested. But I do not see anything that is alarming or would cause me to tell you to rush to be seen. I think it looks like a well-healing Mohs site. "This answer has been solicited without seeing this patient and
cannot be held as true medical advice, but only opinion. Seek in-person
treatment with a trained medical professional for appropriate care."