Retainer brite has been shown to be safe with Clear aligners on a daily use schedule. Just be sure the tablets are not dissolved in Hot water but rather luke warm to room temperature. Patients have reported that aligners still stain and have a slight odor even with regular use.I have found, However, the best way to keep the aligners clean from bacteria, viruses and fungi is with the use of a product called OAP Cleaner. OAP provides instant cleaning of Invisalign and it takes only 60 seconds to use. The carefully formulated, proprietary cleaning solution is effective at cleaning and sanitizing all types of orthodontic appliances. It has clinically been shown to kill 99.99% of all viruses, bacteria, fungi and germs on contact. It also removes stains, plaque and offensive odors. The use of a brush to scrub and rid these critters and plaque off of your alignerstogether with OAP to sanitize and clean your aligner is the way to go.OAP is BPA, persulfate and chlorine-free, and is completely safe to use on Invisalign, as well as Invisalign storage containers. It is a gentle and mild cleaning agent that won’t cause discoloration of the plastic or result in abrasion of any surface material.