If the idea behind the science is that it would be able to speed up the process in which macrophages holding pigment are removed, wouldn't it be equally effective for any dermal pigmented lesions trapped in macrophages? Theoretically, if it works for tattoos, that is. I mean, skin penetration aside, topical agents today only inhibit future pigment and peel epidermal skin layers, it does nothing for pigment already existing in dermis anyway, right?