After Hyaluronidase - How Long to Wait Before Getting Fillers Again?

Question

I got my restylane filler dissolved with hyaluronidase and after 4 days, my doctor gave me some more to correct the defect. Is that ok to have another shot of filler within 4 days of dissolving the previous filler with the hyaluronidase?

Ritu Chopra, MD · Answer

I think there should be a delay of one month after dissolving filler with Hyaluronidase.  We have to avoid the mentality of "Fill me up!  Now take it away!  Fill it more!" and so on.  Injections, like surgery should be a considered, cautious, sober decision uninfluenced by urges and the need for immediate gratification.

Raffy Karamanoukian, MD, FACS · Answer

Filler migration, swelling, and granulomas can cause significant discomfort and cosmetic ramifications. Our office specializes in the use of enzymes and filler reversal techniques without hyaluronidase to help improve the results of botched cosmetic fillers, whether caused by Juvederm, Restylane, or foreign fillers. Our plastic surgery institute provides expertise in filler removal. We begin by examining the facial fillers and assessing the likelihood of fluctuance or liquid volumization. If appropriate, we use Hylenex, or other filler reversal agents to reduce swelling and filler migration. Hylenex can be targeted into the areas of concern using multiple layered injection techniques. If the filler does not completely resolve, then additional concentrations may be employed. The technique has the potential to reduce the filler and may slightly impact normal hyaluronic acid. Treatments are repeated and results can improve immediately and with time.

Best, 
Dr. Karamanoukian
Realself100 Surgeon

Ron Shelton, MD · Answer

the science of clinically using hyaluronidase is still being worked out.  How long it lasts is questionable. I would wait at least a week if not a month before injecting more filler to even it out. Otherwise, injecting the new filler in an area injected with hyaluronidase too soon, may produce more thinning than desired of the new filler.

Samir Shureih, MD · Answer

Yes it is ok. Hyalurinadase is absorbed with in an hour..............................................

Marc Cohen, MD (retired) · Answer

Hyaluronidase works almost immediately and is absorbed by your system quickly.  To be safe I ask my patients to wait about a week before re injection.  The reason for this is that hyaluronic acid fillers (like Juvederm and Restylane) often cause some swelling.  Even though the hyaluronic acid fillers will be gone within an hour,  the swelling may persist.  That swelling normally is gone by one week.

	Hope this helps.

After Hyaluronidase - How Long to Wait Before Getting Fillers Again?

Answers (5)

Answer: Hyalurinidase

Answer: Hyalurinidase

Answer: Hyluronidase is absorbed very quickly

Answer: Hyluronidase is absorbed very quickly

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Everything you need to know about Hyaluronidase

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After Hyaluronidase - How Long to Wait Before Getting Fillers Again?

Answers (5)

Answer: Hyalurinidase

Answer: Hyalurinidase

Answer: Hyluronidase is absorbed very quickly

Answer: Hyluronidase is absorbed very quickly

Browse related questions

Recommended reading

Everything you need to know about Hyaluronidase

Our mission is to create a world where every investment in modern beauty is Worth It.