Thank you for sharing your concern. From your description and photo, the area that tends to create the “sad” or downward appearance is usually a combination of: Downturned corners of the mouth Loss of support in the lower cheek and jawline Early jowl formation Volume loss around the chin and marionette lines For someone wanting the under-mouth area to look more lifted and “happy” rather than pulled downward, I would generally think about treatment in layers rather than trying to fill the crease directly. The options that usually help the most 1. Botox for the depressor anguli oris (DAO) muscles A small amount of Botox can relax the muscles that pull the mouth corners downward. This is often one of the simplest ways to create a subtle upward turn to the corners of the mouth. 2. Filler for structural support Instead of placing filler only in the fold, a better result often comes from adding support to the pre-jowl area and chin. This can soften the marionette shadow and improve the contour of the lower face without making the mouth look heavy. 3. Jawline support If there is mild sagging along the jawline, strategically placed filler can improve the transition from the chin to the jaw and reduce the “pulled down” look. What I would avoid Trying to place a large amount of filler directly into the marionette lines or the crease under the mouth can sometimes make the lower face look puffier or heavier, which is the opposite of the lifted effect most people want. Based on your photo Your concern appears to be mild to moderate lower-face descent rather than severe skin laxity, so I would lean toward DAO Botox combined with conservative chin and pre-jowl support as the most natural-looking approach. Procedures such as thread lifts or surgery are usually reserved for more significant sagging. The encouraging part is that this type of “sad mouth” appearance is often quite treatable with relatively conservative treatments, and the best results usually come from restoring support around the mouth and chin rather than chasing the crease itself.