Pain thresholds vary by patient, but most men and women do not find injectable dermal fillers, such as Restylane, Juvederm, and Volbella, to be particularly painful. We try and perform injection techniques that minimize any pain as well as the number of needle sticks. Almost all injectable dermal fillers contain the anesthetic lidocaine in the formulation that makes the injections less uncomfortable. If you are getting a liquid facelift and have a low pain threshold — or are just nervous about the procedure — your doctor can apply a numbing cream to your skin. We also offer nitrous oxide treatment at an additional cost if it is necessary but find that 99% of our patients do just fine. Please consult a board-certified dermatologist who is an expert at liquid facelifts and bring up your concerns about pain during your meeting. He or she will find you the right solution so you can get the nonsurgical rejuvenation you want without any undue discomfort.