There are two types of Juvederm: Ultra and Ultra Plus. Ultra Plus is thicker and slightly more cross linked than Ultra. Both are made of the same substance, called hyaluronic acid, which is a collection of molecules that retain water. Other fillers that are made of hyaluronic acid include: Perlane, Restylane, Prevelle, and Hydrelle, all lasting between 3-9 months. These fillers are generally best for fine lines, and mild to moderate folds of the face. However, for volume replacement, structure, and lifting, as areas like the jowls require, I prefer a more robust product, like Radiesse. Radiesse, made of calcium hydroxylapatite, is injected into the sub-dermal layer of the skin and can integrate with your bone structure without quickly dissolving. This results in both collagen replacement and collagen stimulation. By returning volume to various areas alongside and underneath sagging skin, as seen in jowls, one can make the areas appear tighter and more lifted. Lastly, because of its thicker consistency, Radiesse sits in mild-deep indentations better [almost as if it were an injectable transplant], and lasts longer. Correction can be seen for up to 18 months. If you have considered your options and elect to take a non-surgical route, fillers are among your best alternatives.