Juvederm or Other Filler for Parentheses Around Mouth?

My short answer is that I think you're making a great choice with Juvederm in this area. The options include Juvederm Ultra, Juvederm Ultra Plus, Restylane, Perlane, Collagen, Radiesse, and your own fat, among others. The reasons why I don't like the others as my first choice in this area are:
Fat: obviously safe (it's your own fat), and what is left after about 6 months is permanent (around 50% of the injected fat is absorbed by 6 months). But you usually need some type of anesthetic, in the OR, to do it well, so there is more cost; swells more than the off-the-shelf products, so there is more downtime.
Radiesse: Great product for very, very deep parenthesis (nasolabial folds) but in my judgement better for areas that need volume, like cheeks or hands. More expensive that Juvederm, but still a nice product if injected properly by an experienced injector.
Collagen: becoming less and less utilized-- usually need a skin test and the results are usually no better than Juvederm, which does not require a skin reaction test/
Restylane: this is the big competitor, and I think many folks would use Restylane as their first choice which is perfectly acceptable and they can get very nice results with it. The reason I prefer Juvederm Ultra to Restylane is that Juvederm Ultra has more cross-linking (means it will typically last longer, at least in my experience), is softer in consistency while Restylane is a bit more granular, and Juvederm Ultra I find is a bit more hydrophilic (attract more water) which means it can plump up the areas that you inject it in a bit more.
Perlane: made by the same company as Restylane, just a thicker product

Juvederm Ultra and Juvederm Ultra Plus are the same thing except Ultra Plus is a bit thicker, thought to last longer.

I hope that helps, Good luck!

Dr. Salemy

It would be helpful to see your picture to give you a little more input, but yes, typically Juvederm is what I would recommend for the nasolabial folds.  If they are deep, I typically would go with Juvederm ultra plus to give you the most bang for your buck as you say.  It is also safe which is even more crucial. 
However, often times midface volume loss is actually the true problem that needs to be addressed first (with Voluma) and will give significant lift to the nasolabial folds while also fixing other issues such as hallowing in the cheek area and bags under the eyes, allowing you to reduce the amount of nasal labial fold filler that you even need. That is why an evaluation is crucial in person with somebody who does aesthetic medicine regularly.
Hopefully you have good trust and faith in your dermatologist and you are just doing a little extra research on the topic in general. If not, find a provider that you trust.