Propecia and neurological damage?

Question

Dear Drs, I am 26 years old and have been taking Propecia for 2 years now without any side effects. I read in an online forum that Finasteride through inhibition of allopregnanolone in the CNS can cause neurological damage and lead to MS or Alzheimer or other issues. I don't believe what I read on online forums which is why I really appreciate your kind opinion. Does Propecia cause damage to the brain or cause MS or Alzheimer? By how much does it reduce allopregnanolone levels in brain and spine ?

Ross A. Clevens, MD, FACS · Answer

Thank you for your question. Please work with a board certified facial plastic surgeon to develop a hair restoration plan tailored to you.
Best wishes,

Daniel Danyo, MD · Answer

I have not heard of neurologic side effects since as Alzheimer's and MS with Finasteride application.  I have many of my patients take it Monday thru Friday and not on the weekends.  I have spoken with other hair restoration specialists who do the same.  This can give the hormone systems that could be affected a little timeout without changing the effectiveness.  Consult with your physician about any change in dosage intervals.

David Perez-Meza, MD, FISHRS · Answer

Great question, We did a Propecia hair loss study and I have read Propecia studies and I am not aware of that possible neurological side effect. You should contact the doctor  that prescribed the medication for further discussion. Good luck

William Rassman, MD (retired) · Answer

It is known that finasteride does interact with brain function in some individual and it is a known rare side effect. I don't believe there is evidence for a connection to Alzheimers or MS

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