Yes, it is perfectly safe to utilize Retin-A during the time period you are having microdermabrasion performed. In fact, Retin-A and microdermabrasion complement each other perfectly to provide optimal results for all skin concerns such as hyperpigmentation, acne, fine lines and wrinkles, skin tone and skin texture. After a microdermabrasion your skin may feel more sensitive because the top layer has been exfoliated and products with active ingredients such as Retin-A may tingle or sting when you apply the product the post treatment. However, the products are able to penetrate deeper into the skin after an exfoliating treatment such as a microdermabrasion and bring more benefits to your skin. You do not need to discontinue the use of Retin-A before or after a microdermabrasion treatment. If on the rare instance you were to experience any signs of excessive irritation and inflammation you could discontinue the use of Retin-A for 2-3 days post treatment to allow your skin to calm down and then begin using Retin-A again regularly. Microdermabrasion is a safe, non-invasive exfoliation method that removes and vacuums dead skin cells from the skin revealing fresh, healthy skin. Softer, smoother skin will be visible after one treatment and results will continue to advance after additional treatments. This procedure promotes new cell growth and vascular circulation under the skin resulting in healthier and firmer skin. Retin-A, medically known as Tretinoin, is a derivative of Vitamin A which stimulates faster cell turn over providing exfoliation to the skin. It is common for patients to report skin irritation such as redness, peeling or sensitivity when they first being the use of a Retin- A. The skin will adjust and become more tolerant as the patient continues to use the Retin-A as instructed. As a result the skin becomes smoother with decreased fine lines, wrinkles, and hyperpigmentation.