Is Microdermabrasion Safe While on Retin-A?

It is not uncommon to use both Retin-A and other hydroxy acids simultaneously with microdermabrasion treatments. But most doctors will likely stop your Retin-A treatment either two weeks or a couple of days before your first microdermabrasion treatment. Note that since you have been on Retina-a, you may have more redness and scabbing after microdermabrasion than if you were not on Retin-A. 

Microdermabrasion and Retin-A.
Retin-A is a proprietary name for tretinoin. The active ingredient is a derivative of Vitamin A and stimulates the cell cycle, thereby inducing exfoliation and deposition of linear collagen in the dermis.
In the early stage of treatment, tretinoin can cause redness, exfoliation, and sensitivity of the skin. As the treatment progresses, the skin will increasingly become tolerant of the Retin-A. The result, a smoother complexion with eradication of fine lines and increased skin resiliency.
Microdermabrasion is a mechanical form of exfoliation. There are many variants. In our Santa Monica office, we utilize two more predictable and effective treatment modalities of mechanical exfoliation. The first is a diamond microdermabrasion that we use routinely with Retin-A treatment. Second, we use a water based exfoliation that infuses enzymes and acids to loosen cellular and pore debris prior to exfoliation to effect a more effective treatment without the intense abrasive effects.