Azzalure vs. Botox: which is better?

on Fox today there's an announcement that Botox has a new competitor in Britain called "Azzalure" sounds like it's Botox (botulinum). Do you expect it to be the same, better, or worse than Botox?

Doctor Answers 7

Azzalure or Botox?

This is a great question, and it gets into the naming of different drugs in different countries. In the U.S., we have Botox, Dysport and Xeomin. The same drugs in most parts of Europe are known as Botox (or Vistabel), Dysport or Azzulare, and Xeomin or BoCotture. So what you need to know is the same product may have different names in different countries. But the drugs are the same – so Dysport = Azzulare, no matter what the label says.

Depending upon who is injecting the product and their experience, someone might like Botox more; someone else might prefer Dysport or Azzulare. The biggest difference is when you use these, you need to understand that when mixing them, we have to use different dilutions of saline to mix them – which should be of no concern to you – but should be to the clinician. More Dysport units are needed than Botox units for each indication – but this does not mean there is no difference. Twenty units of Botox equal about 60 units of Dysport; the units are not interchangeable, so this is the way it is. Depending upon the injector, you can get great results with both.

Find a board-certified dermatologist or plastic surgeon, and learn more about this from them.

Nashville Dermatologic Surgeon
4.0 out of 5 stars 18 reviews

Azzalure vs Botox

I have no experience with Azzalure and have been very happy with Botox injected in my patients

Renato Saltz, MD
Salt Lake City Plastic Surgeon
5.0 out of 5 stars 15 reviews

Azzalure is Botulinum toxin type A

Azzalure is a botulinum toxin type A that just recently received marketing approval in the UK. Azzalure is made by Ipsen, the same company that makes Dysport, which was finally approved for use in the USA by the FDA at the end of April. Dysport has been in use nearly worldwide for the past 20 years and has a good history of consistency and safety. Dysport will be marketed in the US by Medicis, the makers of Restylane and Perlane, while Azzalure will be marketed by Galderma.

Azzalure and Dysport have the same indications as Botox. There is no discrete information currently available on how Azzalure compares to Botox in terms of cost, dosing and duration of muscle relaxation.

Better than Botox? For now it is safe to say Azzalure is comparable to Botox.

Look for Dysport, likely to be known in the US as Reloxin in the next 3 to 6 months.

Good Luck, kit09.

Anifat Balogun, MD
Seattle Otolaryngologist

Azzalure is a type of Botulinum Toxin

Azzalure is a brand name for a formulation of Botulinum Toxin Type A . The same material that is found in Botox.

In the USA the brand name for Azzalure is Dysport. In other words the active ingredient in Azzalure is exactly the same as Dysport.

Dysport recently received FDA approval for use in the USA. Dysport is available through a company by the name of Medicis. This is the same company that makes Restylane and Perlane.

Even though the dose required to achieve a desired result is different that Botox, Dysport functions in essentially the same way.

Undoubtedly some patients will respond better to Dysport while others will respond better to Botox.

Each manufacturers will most likely claim to have the better product. However, only time will tell if one of the products is superior to the other.

Good luck with your procedure.

A. Peter Salas, MD
Manhattan Plastic Surgeon

Azzalure (Dysport) vs Botox

Thank you for your question. Azzalure is known as Dyport in the US. Both Botox and Dysport are very effective and work in the same fashion. More imporant than which product is who is injecting. I train other injectors on the safe and effective use of Botox (and other injectables) and I do find that for the core aesthetic physicians (e.g. plastic surgeons and dermatologists) have the best foundation to learn how to inject. For non-core physicians or nurses, I spend a lot more time focusing my teachings on assessment and the underlying anatomy. It is not something they get a lot of training in during their medical training. Most of Botox complications that reported is usually due to technique and inadequate assessment. For the best results and least complications, would strongly recommend that you stick with a board certified plastic surgeon or dermatologist who does a high volume of injectables as part of their practice.

Young R. Cho, MD, PhD
Houston Plastic Surgeon
4.8 out of 5 stars 36 reviews

Azzalure vs. Botox: which is better?

Botox was the First on the Market followed by Dysport and Now Xeomin.
All 3 are Botulinum Toxins but with minor modifications to the structure but not the function.
They are known by different trade names in different countries e.g. Azzalure and Vistabel

Naveen Somia, MBBS, PhD, FRACS
Sydney Plastic Surgeon
5.0 out of 5 stars 73 reviews

Azzalure is Dysport

Dear Kit

Don't get too excited. Azzalure is Dysport, a botulinum toxin A product just like BOTOX is a botulinum toxin A product. Galderma has licensed with product from Ipsen for distribution of this product for aesthetic indications into the UK, the European Union, and certain parts of Eastern Europe and the Middle East. Medicis, the company that markets Restylane and Perlane, owns the rights to distribute dysport in the United States under the trade name Reloxin. FDA approve for Reloxin is anticipated at any time now.

Azzalure is not better or worse than BOTOX but it is different. One unit of Azzalure is not the same as one unit of BOTOX. It is more likely that 2 to 4 units of Azzalure will produce a similar muscle relaxing effect as 1 unit of BOTOX. However, Azzalure may diffuse differently than BOTOX. So there will be a big learning curve for doctors as they begin to use this new product. Competition is a good thing but not hold your breath that this new botulinum toxin A will spark a price war.

Kenneth D. Steinsapir, MD
Beverly Hills Oculoplastic Surgeon
4.9 out of 5 stars 26 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.