How Much Hyaluronidase Needed to Dissolve Juvederm in Tear Trough?

Question

The doctor injected Juvederm in my tear troughs that I didn't ask for 2 weeks ago. He insisted I would love it and if not he can dissolve it. He injected 0.15cc only. 0.075cc on each side. Left side was very bruised and the bruise is almost gone by now. I have some swelling under my left eye. My lashes touch the skin under my eyes now as it's fuller. The doctor now says he didn't inject the filler in the tear troughs but my cheeks. How much hyaluronidase is needed to dissolve the filler?

Kenneth Hughes, MD · Answer

0.15 cc in a dilution of 150 units/ml would be 22.5 U.  This may be a reasonable starting dose.  Some use 50 U as a starting dose.

Nima Shemirani, MD · Answer

Dear alenka21

	
		The simple answer: enough to dissolve what you want
	
		You can see the results pretty quickly
	
		If you are unhappy, go back to your injector and ask for the hyaluronidase, just be sure you want it dissolved


	Best regards,

	Nima Shemiani

Sam Naficy, MD, FACS · Answer

It depends on the amount of product to break down and the desired effect. Could be equal or less. It is variable and ultimately takes a very small amount to do the job.  .015 ML of Juvederm is a very small amount!  Other than the obvious bruise It's hard to tell from your photos exactly where the product was placed. It's probably best to let your provider make that decision.

Jose Rodríguez-Feliz, MD · Answer

It really depends on the amount of filler in the area and how much you are looking to dissolve. Most surgeons will use between 0.1cc to 0.3cc. The enzyme starts to work pretty fast. If you are looking to dissolve some filler because of asymmetry or you just don't like it, then a conservative amount is preferred first and you can always do more if you want more. On the other hand, if this is an emergency, meaning you had an arterial injection and your skin is getting compromised, I would use a high dose immediately (0.3cc) to start.Hope this was helpful. Good luck!

Benjamin Barankin, MD, FRCPC · Answer

A highly trained and experienced injector such as a dermatologist will know based on how much filler has been put in, how much hyaluronidase is required. ~ Dr. Benjamin Barankin, Toronto Dermatology Centre.

How Much Hyaluronidase Needed to Dissolve Juvederm in Tear Trough?

Answers (6)

Answer: How much hyaluronidase to dissolve HA fillers

Answer: How much hyaluronidase to dissolve HA fillers

Answer: How much hyaluronidase is required

Answer: How much hyaluronidase is required

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How Much Hyaluronidase Needed to Dissolve Juvederm in Tear Trough?

Answers (6)

Answer: How much hyaluronidase to dissolve HA fillers

Answer: How much hyaluronidase to dissolve HA fillers

Answer: How much hyaluronidase is required

Answer: How much hyaluronidase is required

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Recommended reading

Everything you need to know about Juvederm

Our mission is to create a world where every investment in modern beauty is Worth It.