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Posted underSpironolactone For Acne q&a

Is irregular menstrual bleeding on Spironlactone a problem?

KatJDMar 28, 2014
Hi, I have taken 100mg spironalactone for 16 months for adult acne, and 5 months ago increased to 200mg as I was also diagnosed with androgenetic alopecia. I am a little worried as my periods have now become slightly irregular (1-2 bouts of bleeding between periods). Is this ok? I'm worried I'll have to reduce my dose - spironalactone is my only option (I spent 15 years on Dianette and Yasmin until they caused melasma on my forehead). Could you advise me at all please? Many thanks.

Answers (1)

From board-certified doctors and trusted medical professionals
Dr. Reuel Aspacio, MD, FAAD - Account Suspended
Board Certified Dermatologist
Answered on Feb 20, 2020
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Melissa Chiang, MD, FAAD

I have found spironolactone to be reliably effective in treating hormonal acne.  It typically takes 2 months to see results from spironolactone; you may see continued improvement for a few months after that. 

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Ken Landow, MD

No one knows whether saw palmetto actually works...in several studies it was no different than a placebo...its proponents believe it functions to block conversion of testosterone into its active form (DHT) while others credit it with anti-inflammatory effects, a blocker of the androgen receptor...

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Melissa Chiang, MD, FAAD

I usually use accutane (along with birth control in female patients) as an "exclusive" medication because:1) accutane is such a powerful and effective medication, it usually does not need any "partners" to help clear up acne2) accutane has a lot of side effects, including, most commonly, dryness...

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