What to Do About Infected Mole?

Moles rarely get infected. If it does it is typically superficial and can be treated with topical antibiotic ointment. However, this could be a more serious issue such as a skin cancer and should be checked by a dermatologist who can advise you.

If it is painful….it is not a mole. (Unless you scratched or traumatized it accidentally.)If it has redness, it can either be something that got a bit infected (like a sebaceous cyst) or it can be one of several dermatologic skin disorders that range from benign (sebborheic) to "pre cancer" (actinic keratosis) to cancer (squamous cell carcinoma.)In general, giving an antibiotic for a skin cancer, as your practitioner did, makes absolutely no sense at all to me, so it sounds like either things were not explained clearly, the antibiotics were given when not needed, or the wrong diagnosis was made. 

I would encourage you to see a dermatologist or plastic surgeon for an evaluation.  Finish the course of antibiotics, but at some point soon, you should have the lesion checked and possibly biopsied. 

It is generally not wise to operate on an infected lesion. Allow the lesion to heal from your injury to it and respond to the adntibiotics. After waiting a period of 2-3 weeks, you can consider having the lesion excised and biopsied.

Since there is no photo of the mole it is difficult to advise you.  Antibiotics generally take a few days to work and you have to be on the correct antibiotic for the infection.  You should seek out a dermatologist rather than a GP.  Amoxicillin is generally not give for an infection like you are describing.  Any mole that is changing in size and color needs to be evaluated by a dermatologist and sent to the laboratory for examination.  Please find a competent and caring dermatologist who is board certified for treatment.