How Much Saline Do You Put into the Botox Bottle

Question

so that if you use a insulin syringe, the recnstiuted Botox is correctly reflected by one unit on the insulin syringe.

Ron Shelton, MD · Answer

Whether the physician dilutes the Botox powder with a diluent of 1, 2, 2.5 or 4 ccs of saline, the important variable which determines your result, is the total number of units given. If doctor B uses a 2cc dilution they will have to give twice the volume of diluted Botox to create the same effect as doctor A who uses a 1 cc dilution.  Both doctors will have administered the same number of units! If the dilution is excessive, then the larger volume might make the Botox travel via gravity or spread of fluid to surrounding areas and there might be an affect on muscles that were not targeted.

Ran Y. Rubinstein, MD · Answer

Allergan recommends mixing 2.5 cc of saline per 100 units of Botox.
There is a wide range of what doctors use--anywhere from 1 to 4 cc per 100 units. I think what is more important in achieving the results you desire is

Skill of injector--who is injecting you?
Make sure using real Botox
Make sure it isn't watered down
Make sure fresh Botox

Good luck!

Scott Trimas, MD · Answer

Typically, botox is diluted from 1 to 4cc of saline depending upon the injector and his or her experience. In my opinion, the most important consideration is how many units are you receiving for a particular area. Inadequate units are the most common reason for a less than desired effect while too many units or injection in the wrong place can cause side effects like eyelid or eyebrow drooping.

Otto Joseph Placik, MD · Answer

I would refer to the package insert when it comes to preparing and injecting Botox for administration.
There are many marks on the insulin syringe and if you are referring to the o.1ml mark than diluting it with 1cc of saline.
I hope that you are a medical professional asking this question with the proper credentialing to prepare this.

Steven Wallach, MD · Answer

Every doctor varies his dilution of botox so that it works for them. I prefer to keep it fairly concentrated.  This usually means 2 cc's of saline so that I get about 50 units per 1 cc syrringe.  Others double that number.

How Much Saline Do You Put into the Botox Bottle

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Answer: Preparing Botox for injection.

Answer: Preparing Botox for injection.

Answer: Botox bottle and saline

Answer: Botox bottle and saline

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How Much Saline Do You Put into the Botox Bottle

Answers (9)

Answer: Preparing Botox for injection.

Answer: Preparing Botox for injection.

Answer: Botox bottle and saline

Answer: Botox bottle and saline

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Recommended reading

Everything you need to know about Botox

Our mission is to create a world where every investment in modern beauty is Worth It.