Will Green Irises Change After Using Latisse?

I've been using Latisse for 9 weeks and I'm seeing wonderful results with it. However, I'm very concerned about iris color change. My iris color is a really pretty green/gold. What is the chance of my iris turning brown?

Doctor Answers 4

Latisse and change in eye color

In the FDA studies leading up to its approval, there were no cases reported of darkening of the iris. HOWEVER, Latisse was serendipitously discovered to cause eyelash growth after ophthalmologists treating glaucoma patients with Lumigan noticed thicker, longer eyelashes in their patients. The ophthalmologists ALSO noted darkening of blue and green irises in some patients.

For this reason, it is recommended that Latisse be applied to only the upper lid, to minimize entry of the drug into the eye.

I counsel all my patients using Latisse that even though the FDA studies didn't show it, eye color can darken. Latisse and Lumigan are the exact same medicine: Bimatoprost.

San Jose Ophthalmologist

Light irises may change color if you have any brown colors within the iris

If you are in doubt about the potential to change color, it is always best to have your eyes examined by a "slit lamp" (magnified lenses especially designed to see details of the eye and iris) exam by an Ophthalomologist.

The culprit that causes the iris to change the color of blue or green eyes is if you have any sign of brown speckling withing the tissue of the iris. Pure green and blue colors are not likely to change to brown.

Shalini Kapoor, MD
Los Angeles Ophthalmologist
5.0 out of 5 stars 3 reviews

Darkening of eye colour

It is a very rare risk but you may experience an increase in brown pigmentation in your irises. However, I haven't noticed this in any of my patients to date, and in fact, a staff member who works at my practice hasn't had this happen to her even though she has green eyes. If you see this happening to you, you should stop using Latisse, however, there is a risk that the change may be permanent.

Jerome Edelstein, MD
Toronto Plastic Surgeon
5.0 out of 5 stars 176 reviews

You are the high risk group but still unlikely

Latisse was discovered when Lumigan, the same medication used for glaucoma, was applied into the eye and some patients had darkening or changing eye color which is permanent in some cases. It is of greatest risk when there is a degree of brown pigment already present.

That being said, there have been no cases reported of darkening of the iris with Latisse and the reason is that it is carefully placed on the lashes and not in the eye if used as directed. Therefore you are probably safe to use Latisse and not have any problems, but it might be best to apply it sparingly to avoid any getting into your eyes. Even if some were to get in your eyes, the chances of pigment changes is still low.

You may wish to discuss this further with your doctor who can help you make the final judgement.

Jon Dishler, MD, FACS
Greenwood Village Ophthalmologist
5.0 out of 5 stars 3 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.