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Botox allergy testing - how much is needed to test for an allergic reaction?

I suspected I had an allergic reaction to Botox previously resulting in full body hives. I wanted to see if I can proceed with Xeomin in the future. I was injected with 2 units of Xeomin intradermaly in the forearm. Is this a realible way to test? Or is 2 units not enough to test thus a full dose can still result in a allergic reaction? Or is it pretty safe to proceed with further injections? I have read an article that suggests a small dose isn't enough to reliably test as it might not be enough to set of a allergy?

Answers (1)

From board-certified doctors and trusted medical professionals
Dr. Natalia Hegedosh, MD
Dr. Natalia Hegedosh, MD
Board Certified Family Physician
Answered on Nov 9, 2026
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