Yes, Phenergan (promethazine) can generally be taken after sleeve gastrectomy, but it should be used with caution and under the guidance of your bariatric team. It's commonly prescribed for nausea and vomiting, which can occasionally occur after surgery, especially in the early stages or if there are issues like dehydration or dietary intolerance. Because Phenergan can be sedating and slow down gastric motility, we typically prefer to use it when other options like ondansetron (Zofran) aren’t effective or appropriate. It's also available in multiple forms—oral tablets, rectal suppositories, and even injections—so depending on your symptoms and tolerance, your provider can choose the best route for you. If you're still early in your recovery or dealing with persistent nausea, it’s important to get to the root of the problem rather than relying solely on medication. In short, yes, it can be used safely, but it should always be done under medical supervision to ensure it’s appropriate for your situation and doesn’t interfere with your healing or hydration.