Can PRP and PRF be used together synergistically in one session as a combo after a hair transplant?

Question

If the answer is yes, I would like to know the full recipe for this combo if possible. How many sessions and what intervals? How much blood to draw? Should the two be combined in the same syringe, or administered separately after spinning them in the centrifuge? Is it possible to damage the hair follicles if they receive too many growth factors? I kindly thank you for your time and effort!

Anna Chacon, MD, FAAD · Answer

Yes, PRP and PRF can be used together synergistically in one session after a hair transplant. These treatments are often combined to enhance the healing process and promote hair growth more effectively.

Here are some details to consider:

Full Recipe and Protocol:

Blood Draw: Typically, about 10-20 ml of blood is drawn for PRP and an additional 10-20 ml may be drawn for PRF, depending on the specific protocol and the area being treated.
Centrifugation: The blood is then spun in a centrifuge to separate the platelet-rich plasma and platelet-rich fibrin. PRP is usually obtained after a faster, shorter spin, while PRF requires a slower, longer spin.
Combination and Administration: After centrifugation, PRP and PRF can be combined. However, they are often administered separately to maximize the benefits of each component. PRP is usually injected first, followed by PRF which has a gel-like consistency and can be used to provide a scaffold for prolonged release of growth factors.

Sessions and Intervals:

Initial Treatment: Typically, an initial series of 3-4 sessions is recommended, spaced 4-6 weeks apart.
Maintenance: After the initial series, maintenance treatments may be done every 4-6 months, depending on the patient’s response and the physician’s recommendation.

Potential for Damage:

Growth Factors: While PRP and PRF are rich in growth factors that promote healing and hair growth, there is generally no risk of damaging hair follicles by receiving too many growth factors. However, it is important to follow a protocol outlined by a qualified physician to ensure safe and effective treatment.

Combining PRP and PRF can potentially offer enhanced results due to the complementary mechanisms of action, with PRP providing immediate growth factor release and PRF offering sustained release and a fibrin scaffold for tissue regeneration.

Thank you for your time and effort in seeking the best information for your hair restoration journey. If you have any further questions, feel free to reach out.

I hope this information is helpful. Please consult with your treating physician to tailor the protocol to your specific needs and conditions.

Ross Kopelman, DO · Answer

Yes, PRP (Platelet-Rich Plasma) and PRF (Platelet-Rich Fibrin) can absolutely be used together in one session to enhance hair transplant results. The combination can provide a more sustained release of growth factors, promoting healing and stimulating hair growth. I typically recommend separate syringes after centrifugation to maintain the integrity of each product. As for how much blood to draw, I usually start with about 15-20ml for PRP and another 10-15ml for PRF.
A good protocol would involve 3 to 4 sessions, spaced about a month apart. This spacing allows your follicles to receive the growth factors without overwhelming them. There’s little risk of damaging hair follicles from receiving too many growth factors, but I prefer a balanced approach with careful timing between sessions to ensure optimal results.
Each patient's situation is unique, so I tailor my approach based on their specific hair restoration needs.

Matt Tahsini, MD · Answer

Hello and thank you for your question.  The bottom line is yes. By doing this you can sometimes help the healing process and hair growth.   It's best to talk to your doctor to see if its a good option for you.  BEst of luck.

Dr. T

Can PRP and PRF be used together synergistically in one session as a combo after a hair transplant?

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Can PRP and PRF be used together synergistically in one session as a combo after a hair transplant?

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Everything you need to know about Hair Transplant

Our mission is to create a world where every investment in modern beauty is Worth It.