Microneedling stimulates the formation of both collagen and elastin fibers in the skin. For the best results, microneedling should be combined with the application of an effective serum. Micro-channels in the skin are created which enhance penetration of topical serums and medications, dramatically increasing their effectiveness. Up to 80% of product can penetrate the skin compared to 7 to 10% with normal topical application. In my office, we use the ProCell Therapies system which combines motorized microneedling with concentrated human growth factor serums made from human stem cells. Our patients also use growth factor serum at home after the office treatment.