Does a Vial of Botox Come Pre-mixed?

Botox does not come pre-mixed. Botox comes in a powder form and is shipped in a small glass vial. It is then mixed with Saline before use. It does not have to be mixed each time it is used, but 100 Botox units are mixed at a time.
Our patients normally have between 20 units and 60 units injected so in many cases a portion of the vial remains for the subsequent patients.

Botox is stored in a cold environment and has no liquid in it when the manufacturer delivers it.
We generally use a minimal dilution as I think more concentrated Botox allows us to use fewer needle sticks.  Others dilute it more, but my concern is that higher dilutions may not last as long.

It is mixed every time it is first opened. The same bottle has enough units of Botox to treat two to three cosmetic units. This rarely is all done on the same patient, and more commonly provides doses for two or three patients.

Botox does not come premixed. It comes freeze dried (kinda like astronaut food). The injector will help pick the dilution of botox depending on the intended application. Once botox is mixed it should ideally be used within 4 hours of reconstitution but this number is controversial. Botox can be made more dilute but can never be made more concentrated (Add saline to product but do not add actually botox to reconstitution).

Botox does not come pre-mixed and needs to be reconstituted with normal saline prior to injection. Once mixed, the effectiveness of Botox can last for a certain period of time. Everyone dilutes their Botox with different amounts of normal saline, thus you should know how many 'units' of Botox that you are receiving and not how many 'cc's'. Good luck.

Botox cosmetic is manufactured by Allergan. This is the same company that manufactures Natrelle breast implants.
Botox is available in the United States in two different packages: Botox Serotype A for cosmetic use and Botox Serotype A for medical use.
Only Botox cosmetic should be used by your physician for the treatment of wrinkles. This is available in a multi-use vial containing a powder of 100 units of Botulinum Serotype A.
In my plastic surgery practice, I constitute the 100 units into 5 cc of sterile normal saline. This allows proper infiltration of botox into the subcutaneous space.

Hi,
Botox comes in a glass vial freeze dried.  It comes in 100 unit vials which need to be "mixed" before use.  The amount of solution mixed varies from physician to physician, from 2cc to 6cc.  The number of total units injected is what determines the effect of Botox.
Dr. P

Botox cosmetic comes as a purified protein - not in suspension. It is reconstituted with some amount of saline - depending on the provider. After it is reconstitued, it should be used within 4 hours - according to the most stringent recommendations. Studies have shown, and it is our experience, that it retains its efficacy far longer than that. I hope this helps!
Dr. Kaufman

Apeeling One, Botox come freeze-dried and needs to be reconstituted. It come in 100 unit and 50 unit vials. It needs to be mixed with preservative-free normal saline. The amount of saline used determines the concentration. I hope this is helpful. David Shafer, MD New York City

Each vial of Botox needs to be prepared for injection by adding fluid. Different offices use different dilutions, all of which are potentially valid. There are pros and cons for using different dilutions, but the key is really how many UNITS are being injected into an area, not how many cc's or vials. See a well-reputed board certified dermatologist or plastic surgeon, and make sure you feel comfortable and know exactly what you are paying for.