Is the PRP hair regeneration permanent, what is the difference between prp and prp hair regeneration?

I am 20 years old and I suffer from genetic hair loss

Doctor Answers 3

Huge difference in PRP alone and Hair Regeneration in results, number of treatments, and long-term sustainability results

Thank you for your question. You didn’t submit a photo, but you’re asking if PRP Hair Regeneration is permanent, and ask about the difference of PRP versus PRP Hair Regeneration. I can certainly understand the reason for your confusion. There are a lot of terms used in this world of hair loss.

I’ll give you a little guidance about this. A little background: I’m a Board-certified cosmetic surgeon and Fellowship-trained oculofacial plastic and reconstructive surgeon, practicing in Manhattan and Long Island for over 20 years. I’m also the founder of TrichoStem™ Hair Regeneration Centers using a technology we developed that includes PRP, but also includes Acellular matrix, and it actually evolved out of the applications originally for hair transplant.

Let’s first answer the question of permanence, which we deal with a lot. Long story short, when we developed TrichoStem™ Hair Regeneration, this was based on developing a process called Hair Regeneration. The reason why we called it Hair Regeneration is when we were doing hair transplant surgery, we would use this platelet-rich plasma (PRP) and extracellular matrix combination to help the wound healing of the donor area, as well as the hair grafts. We noticed periodically that in patients who had thinning hair, the hair got thicker. It became part of a strategy where we would combine the two processes so we would do hair transplant with PRP Acellular matrix, or Hair Regeneration.

What I did over time is look at this potential of treating people who have hair thinning, which we could treat without a transplant, and just use Hair Regeneration. For us, Hair Regeneration meant a process that included PRP or platelet-rich plasma combined in a very specific way with Acellular matrix, Vitamin D and other elements to a total protocol.

Thanks to the popularity of this treatment we developed, we are treating people from all over the world and popularizing the term Hair Regeneration. It can also be referred to as PRP Hair Regeneration. The way we explain our process, we use Hair Regeneration, or now the company we developed to bring this technology close to people outside of our offices in Manhattan and Long Island called TrichoStem™ Hair Regeneration Centers. The idea is, when you think of the word “regeneration”, you’re dealing with thinning hair, and deteriorating hair follicles, so we’re doing regenerating their capacity to grow and to make hair.

What you can also distinguish is PRP alone as a standalone treatment for hair loss, versus TrichoStem™ Hair Regeneration, and for us, it couldn’t be more night and day. When we were developing this treatment, and in the regular routine of using PRP in our practice, as a cosmetic surgeon who does a lot of cosmetic dermatologic treatment, lasers and injectables, we are constantly developing better ways to help people improve their skin. We use PRP routinely every day, all day for: under eye circles, fine lines and wrinkles, acne scars, skin tissue rehab, and helping people with sun damage. My observation is with skin, we are able to get a certain degree of long-term benefit, but when it comes to hair loss, PRP alone can have short-term benefit. You can inject PRP to stimulate hair growth. In other words, you can take a hair follicle that’s not growing due to a prolonged resting stage, for example with androgenetic or male pattern or female pattern hair loss, and you can stimulate growth, but will that hair continue to grow?

In our practice, Hair Regeneration with the combination or PRP, Acellular matrix, Vitamin D and the protocol I developed over several years, we have 5 years of data showing sustainable benefit without repeated injections. There are people who get another injection around 15 months which we refer to as the booster injection, but it is not a requirement. It appears we can help people who have gotten some regrowth from the first Hair Regeneration treatment of very fine hairs, so a lot of those hairs can be responsive to another treatment.

In contrast, PRP alone is routinely done monthly, in some cases weekly, and in other cases 3-6 months. Doctors have different experiences in what they feel is the best thing for their patients. I have found out that sustainability is very important, and patients with hair loss going for treatment where they have injections in their scalp every month often get fatigued, and frustrated not knowing the endpoint, and how long they withstand getting injected monthly, so many of them have come to us to have a treatment we refer to as Hair Regeneration.  I hope this distinction is helpful to you, and helps you learn more on differentiating PRP alone versus Hair Regeneration. I hope that was helpful, I wish you the best of luck and thank you for your question.


New York Oculoplastic Surgeon
4.3 out of 5 stars 69 reviews

Hair loss -- PRP, Progesterone, Viviscal, Rogaine, Finesteride, Spironolactone

Hair loss treatments must be used for life. Nothing is permanent with hair loss and you will eventually lose hair unless you do hair transplantation. I suggest you see an expert for treatment options. Best, Dr. Emer.

Jason Emer, MD
Los Angeles Dermatologic Surgeon
4.9 out of 5 stars 188 reviews

PRP is to be continued for Life

Hello. I understand how stressful it is to be loosing hair. Specially being such a young gentleman. What I can think about whit none to very little side effects is PRP (Platelet Rich Plasma). This procedure consists on getting some of your blood and putting it in a machine that will separate the different ingredients that are in the blood. From those ingredients we take the growth factors and inject them in your scalp. These growth factors will start working in your follicles enhancing your hair and reducing (and even stopping) the rate of your hair loss. If your follicles have not been dormant for too long the hair can regrow.We recommend our patients to do the PRP therapy at least once a year. As any other non-surgical treatments, it is to be continued for life in order to keep having a positive effect on your hair. There are additions they can do to your PRP treatment like Acell.  There are many different treatments that can help you achieve your goals. PRP is only a very good one.Best of lucks on your quest to regenerate your hair!

William Yates, MD
Chicago Hair Restoration Surgeon
4.7 out of 5 stars 19 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.