Will a Deep Laser Peel Make Botox and Juvederm Less Effective?

As one is healing from a laser treatment (either ablative or nonablative) the skin will heal better if it isn't moving as much. Botox helps in decreasing the movement, thereby leading to a better result. The theory is that the newly formed collagen gets laid down better. You must space out Botox about 1 week on either side of a major laser procedure (erbium or CO2 lasers). There has been a report of botox migrating when it was given within 24 hours before a laser treatment presumably due to the edema and swelling.

Treating a patient with Botox and a filler like Restylane, Juvederm, radiesse, Perlane or Evolence can improve the results of laser resurfacing and laser peel. We do this in conjunction with our combined laser resurfacing technique and laser peel results are better foillowing Botox than when Botox is not used before the laser peel.
Anecdotally, laser resurfacing may lessen the duration of the Botox result. There is no scientific proof but some patients who have had surgery or laser resurfacing shortly after Botox injections have reported that the Botox Effect was shorter lasting by a month or so than when Botox alone was used.
However, the benefits of using Botox before a laser peel far outweigh the disadvantage of shorter duration, if in fact that occurs.