Botox or Laser on Deep, Vertical Forehead Creases?

If your creases are as deep as you describe, you will probably need to use several different therapies to smooth out the area enough to satisfy you. Laser resurfacing can erase wrinkles and creases to some degree, but if the creases are deep, that will not be sufficient. Botox would then be used to relax the muscles that are causing the crease, helping it smooth out. If you can still see the creases at this point, I'd recommend adding in a hyaluronic-acid-based filler such as Juvederm or Restylane to fill in the wrinkle. Please consult a board-certified dermatologist, as your wrinkles sound like they require a great deal of expertise to treat. 

It's hard to visualize what your wrinkles look like or which dynamic muscles might be causing them without an in-person consultation or at least seeing photos. Deep creasing does suggest that you may need laser resurfacing and/or hyaluronic-acid-based dermal fillers to even out the furrows. However, Botox could be a first good step because it may be able to quiet the muscles that are causing the wrinkles sufficiently that the skin smooths out. Depending on how deep your wrinkles actually are, Botox might actually be the only step you need. Please consult a board-certified dermatologist to have your wrinkles evaluated and find out which cosmetic procedures can best treat them.