CoolSculpting was developed based on the proven concept of cryolipolysis. Cryolipolysis allows for adipose tissue to undergo controlled cooling, leading to lipolysis – break down of fat cells – without any invasive procedures or damage to nearby tissues. Evidence has shown that non-invasive cryolipolysis for subcutaneous fat reduction does not affect serum lipid levels or liver function tests. Studies have been done where subjects with fat pockets were treated with CoolSculpting and serum lipid levels and liver tests were measured prior to treatment and then at at one day, one week, four weeks, eight weeks and twelve weeks post-treatment. Researchers found no significant changes in mean values for blood lipid levels or liver tests following the treatments. So, in short, the answer is no; having a liver problem will not slow down the process of metabolizing fat after you have had a CoolSculpting treatment.